BENZENETHIOSULFONIC ACID S-PHENYL ESTER Property

Melting point:

36-53 °C(lit.)

Boiling point:

125 °C(Press: 0.01 Torr)

Density 

1.35±0.1 g/cm3(Predicted)

Flash point:

>230 °F

storage temp. 

-20°C Freezer

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Very Slightly)

form 

Solid

color 

Off-White

BRN 

1530592

InChIKey

ATKJLMWDXASAJA-UHFFFAOYSA-N

EPA Substance Registry System

Benzenesulfonothioic acid, S-phenyl ester (1212-08-4)

Safety

Safety Statements 

22-24/25

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

BENZENETHIOSULFONIC ACID S-PHENYL ESTER Chemical Properties,Usage,Production

Uses

S-Phenyl Benzenethiosulfonate is an high potency antifungal thiosulfonate that were tested against Aspergillus niger and Aspergillus flavus.

Synthesis Reference(s)

Journal of the American Chemical Society, 99, p. 4405, 1977 DOI: 10.1021/ja00455a032
Tetrahedron Letters, 10, p. 1239, 1969

Purification Methods

Recrystallise the disulfoxide from EtOH or MeOH. It has also been purified from phenylsulfide impurities by dissolving in CHCl3, washing with aqueous saturated NaHCO3, drying (Na2SO4), filtering, evaporating the filtrate, and the residual oil is passed through a silica gel column (600g) and eluted with hexane/*C6H6 (1L, 4:1, eluting PhSSPh) then *C6H6 (1L) which elutes PhSSO2Ph. [Trost & Massiot J Am Chem Soc 99 4405 1977, Knoevenagel & R.mer Chem Ber 56 215 1923, Beilstein 11 IV 220.]